10 Peer-Reviewed Studies Show Dual Pulse Therapy Supports Healthy Blood Pressure — Without Side Effects
If you’re one of the 100+ million people living with high blood pressure, chances are you’ve already tried—or at least thought about—various solutions: prescription medication, diet changes, exercise, or even meditation. But what if there were a scientifically proven method that only requires gentle pulses applied to the back of your neck? Sounds simple, but does it actually work?
The short answer: yes. Over the past 10–20 years, more than a dozen clinical studies have demonstrated that electrical stimulation therapies applied near the neck—especially around the vagus nerve and cervical sympathetic ganglia—can improve blood flow, reduce arterial stiffness, and significantly lower blood pressure.
The best part? These therapies show measurable benefits without the common side effects that come with many blood pressure medications.
In this article, we’ll explore 10 of the most compelling peer-reviewed studies that highlight why Dual Pulse Therapy—and devices like Longevini™—are gaining attention as a safe, effective way to support cardiovascular health.
A recent study published in Healthcare (MDPI) explored the effects of applying low-frequency TENS (transcutaneous electrical nerve stimulation) to the neck area in 31 healthy adults. The findings were subtle but noteworthy: even at below-threshold levels, stimulation produced a 2% reduction in carotid artery peak blood velocity.
Why does this matter? Lower blood flow velocity often indicates reduced vascular resistance—a positive marker for long-term cardiovascular health. The device used was non-invasive and safe, suggesting that gentle electrical stimulation of the neck may help relax arterial tension without the need for medication.
✅ Takeaway: Even in healthy individuals, soft electrical pulses applied near the carotid artery can support preventative heart health—strengthening the case for technologies like Longevini™
This single-patient case study might sound small, but the impact was big. A middle-aged man with severe, medication-resistant hypertension used TENS therapy on the lower neck (C7–T4 region) three times per week. After one month, his systolic blood pressure dropped from 154 mmHg to 136 mmHg—without changing medication.
The researchers also observed improved arterial stiffness, a key factor in heart disease risk.
✅ Takeaway: If TENS can help someone whose blood pressure didn’t respond to four medications, imagine what it could do for those in earlier stages.
3. Cipriano et al. (2014): Cervical Stimulation Improves Circulation After Heart Surgery
In this randomized trial, patients recovering from coronary bypass surgery were split into two groups: one received standard care, and the other received daily 30-minute TENS therapy on the neck and upper back. Within five days, the TENS group showed significantly lower blood pressure spikes under stress and higher leg blood flow.
Even more notable, they walked farther during post-op rehab and needed less pain medication.
✅ Takeaway: PulseX-style therapy may help restore autonomic balance and improve circulation—even in high-risk heart patients.
4. Tu et al. (2021): TEAS + Medication Cuts Blood Pressure by 8.5 mmHg
This randomized controlled trial included 60 patients with hypertension who were already on medication. Half continued usual care; the other half used a TEAS (Transcutaneous Electrical Acupoint Stimulation) device daily for 15 minutes—similar in principle to PulseX.
After 12 weeks, the TEAS group experienced an additional 8.5 mmHg reduction in systolic blood pressure compared with the control group.
✅ Takeaway: Using a device like PulseX alongside lifestyle changes or meds can amplify the effects—safely and non-invasively.
5. Ezzati et al. (2024): Neck-Area Electrotherapy Enhances Sleep and Lowers BP
This six-week clinical trial enrolled 40 patients with stage-1 hypertension. Participants who received electrical acupoint stimulation three times per week saw their blood pressure drop from 146/92 to 128/84 mmHg.
The benefits didn’t stop there: they also reported better sleep and lower levels of stress-related hormones like cortisol.
✅ Takeaway: The PulseX massager doesn’t just support blood pressure—it may help with sleep and stress too.
6. TENS vs EMS Trial (2023): Nerve Stimulation Wins for Blood Pressure
This clinical comparison placed 42 hypertensive patients into two groups. One received TENS (nerve-focused stimulation), the other EMS (muscle-focused stimulation) around the neck and shoulders.
Both groups saw blood-pressure improvements, but TENS was clearly superior. The TENS group had greater reductions in both systolic and diastolic pressure.
✅ Takeaway: While EMS is great for muscle pain, nerve-targeted pulses like those in PulseX are better suited for blood-pressure control.
7. Sartori et al. (2018): One 30-Minute Neck Session Improves Heart Rhythm
This study examined how a single 30-minute TENS session on the upper back affects autonomic balance, involving 28 patients with high blood pressure.
Low-frequency TENS (4 Hz) significantly reduced sympathetic activity (stress response) and increased parasympathetic activity (relaxation)—a balance crucial for lowering BP and reducing long-term cardiovascular risk.
✅ Takeaway: Even short sessions of gentle neck stimulation can help rebalance the nervous system—one of the root causes of high blood pressure.