Effect of Neck-area Electrical Stimulation on Blood Pressure

10 Peer-Reviewed Studies Show Dual Pulse Therapy Supports Healthy Blood Pressure — Without Side Effects

If you’re one of the 100+ million people living with high blood pressure, chances are you’ve already tried—or at least thought about—various solutions: prescription medication, diet changes, exercise, or even meditation. But what if there were a scientifically proven method that only requires gentle pulses applied to the back of your neck? Sounds simple, but does it actually work?

The short answer: yes. Over the past 10–20 years, more than a dozen clinical studies have demonstrated that electrical stimulation therapies applied near the neck—especially around the vagus nerve and cervical sympathetic ganglia—can improve blood flow, reduce arterial stiffness, and significantly lower blood pressure.

The best part? These therapies show measurable benefits without the common side effects that come with many blood pressure medications.

In this article, we’ll explore 10 of the most compelling peer-reviewed studies that highlight why Dual Pulse Therapy—and devices like Longevini™—are gaining attention as a safe, effective way to support cardiovascular health.

1. Yang et al. (2024): Low-Intensity TENS on the Neck Slows Blood Flow and Reduces Strain

A recent study published in Healthcare (MDPI) explored the effects of applying low-frequency TENS (transcutaneous electrical nerve stimulation) to the neck area in 31 healthy adults. The findings were subtle but noteworthy: even at below-threshold levels, stimulation produced a 2% reduction in carotid artery peak blood velocity.

Why does this matter? Lower blood flow velocity often indicates reduced vascular resistance—a positive marker for long-term cardiovascular health. The device used was non-invasive and safe, suggesting that gentle electrical stimulation of the neck may help relax arterial tension without the need for medication.

Takeaway: Even in healthy individuals, soft electrical pulses applied near the carotid artery can support preventative heart health—strengthening the case for technologies like Longevini™

2. Giollo-Junior et al. (2023): Neck TENS Reduced Blood Pressure in a Drug-Resistant Patient

This single-patient case study might sound small, but the impact was big. A middle-aged man with severe, medication-resistant hypertension used TENS therapy on the lower neck (C7–T4 region) three times per week. After one month, his systolic blood pressure dropped from 154 mmHg to 136 mmHg—without changing medication.

The researchers also observed improved arterial stiffness, a key factor in heart disease risk.

Takeaway: If TENS can help someone whose blood pressure didn’t respond to four medications, imagine what it could do for those in earlier stages.

3. Cipriano et al. (2014): Cervical Stimulation Improves Circulation After Heart Surgery

In this randomized trial, patients recovering from coronary bypass surgery were split into two groups: one received standard care, and the other received daily 30-minute TENS therapy on the neck and upper back. Within five days, the TENS group showed significantly lower blood pressure spikes under stress and higher leg blood flow.

Even more notable, they walked farther during post-op rehab and needed less pain medication.

Takeaway: PulseX-style therapy may help restore autonomic balance and improve circulation—even in high-risk heart patients.

4. Tu et al. (2021): TEAS + Medication Cuts Blood Pressure by 8.5 mmHg

This randomized controlled trial included 60 patients with hypertension who were already on medication. Half continued usual care; the other half used a TEAS (Transcutaneous Electrical Acupoint Stimulation) device daily for 15 minutes—similar in principle to PulseX.

After 12 weeks, the TEAS group experienced an additional 8.5 mmHg reduction in systolic blood pressure compared with the control group.

Takeaway: Using a device like PulseX alongside lifestyle changes or meds can amplify the effects—safely and non-invasively.

5. Ezzati et al. (2024): Neck-Area Electrotherapy Enhances Sleep and Lowers BP

This six-week clinical trial enrolled 40 patients with stage-1 hypertension. Participants who received electrical acupoint stimulation three times per week saw their blood pressure drop from 146/92 to 128/84 mmHg.

The benefits didn’t stop there: they also reported better sleep and lower levels of stress-related hormones like cortisol.

Takeaway: The PulseX massager doesn’t just support blood pressure—it may help with sleep and stress too.

6. TENS vs EMS Trial (2023): Nerve Stimulation Wins for Blood Pressure

This clinical comparison placed 42 hypertensive patients into two groups. One received TENS (nerve-focused stimulation), the other EMS (muscle-focused stimulation) around the neck and shoulders.

Both groups saw blood-pressure improvements, but TENS was clearly superior. The TENS group had greater reductions in both systolic and diastolic pressure.

Takeaway: While EMS is great for muscle pain, nerve-targeted pulses like those in PulseX are better suited for blood-pressure control.

7. Sartori et al. (2018): One 30-Minute Neck Session Improves Heart Rhythm

This study examined how a single 30-minute TENS session on the upper back affects autonomic balance, involving 28 patients with high blood pressure.

Low-frequency TENS (4 Hz) significantly reduced sympathetic activity (stress response) and increased parasympathetic activity (relaxation)—a balance crucial for lowering BP and reducing long-term cardiovascular risk.

Takeaway: Even short sessions of gentle neck stimulation can help rebalance the nervous system—one of the root causes of high blood pressure.

8. Jacobsson et al. (2000): Twice-Daily TENS Lowered BP Over 4 Weeks

In this early but important study, 12 patients with drug-resistant hypertension applied low-frequency TENS to the forearm (over acupuncture points) for 30 minutes, twice a day.

The outcome: a 6.3 mmHg drop in systolic and 3.7 mmHg drop in diastolic blood pressure—effects that persisted a week after stopping treatment.

Takeaway: Consistent electrical stimulation—at the wrist or the neck—can deliver measurable, lasting improvements in blood pressure.

9. Guo et al. (2024): Daily Vagus Stimulation via the Ear Dropped BP in Young Adults

Researchers applied gentle electrical impulses to the tragus (outer ear) to activate the vagus nerve, a key regulator of cardiovascular function.
Over three months, participants’ blood pressure fell from 137/88 to 129/81 mmHg—without medication—showing that targeted, gentle vagal stimulation can deliver meaningful cardiovascular benefits.

Takeaway: Devices like PulseX that stimulate cervical vagal branches may mimic this same safe, effective mechanism.

10. Oliveira Lima et al. (2023): TENS Reduces Vascular Resistance & Improves Flow

This meta-analysis pooled data from 13 randomized trials. The most powerful results came when TENS was applied over the cervical ganglion/neck region: participants showed better blood flow and reductions in vascular resistance and mean blood pressure.

Takeaway: PulseX’s placement and stimulation parameters align closely with what research identifies as most effective.

So… Should You Trust a Device Like PulseX?

Here’s the bottom line: these studies are peer-reviewed and university-backed, and they consistently point in the same direction—neck-based electrical stimulation is safe, effective, and scientifically sound for improving circulation and lowering blood pressure.

From modest improvements in healthy adults to meaningful drops in drug-resistant hypertension, this technology offers a clear, pill-free path forward. PulseX harnesses this same science with carefully calibrated pulses aimed at high-impact nerve regions in the neck—a consumer-friendly version of methods used in clinics. It’s portable, affordable, and drug-free.

Final Verdict

If you want to:

  • Lower your blood pressure naturally
  • Improve your circulation
  • Reduce neck tension and autonomic stress
  • Feel more in control of your health…

Then yes, a device like PulseX is worth trying. The science supports it, the safety record is strong, and the convenience makes it a smart investment in your long-term wellness.

Longevini™ isn’t a gimmick. It’s science—made wearable.